Olumiant 4mg Tablet (Baricitinib 4mg)

INTRODUCTION

OLUMIANT 4 contains Baricitinib which belongs to a group of medicines called Janus kinase inhibitors, which reduces inflammation. It is indicated to treat moderate to severe rheumatoid arthritis and atopic dermatitis (atopic eczema). Rheumatoid arthritis is an inflammatory disease of the joints. This medicine can also be used alone or together with some other medicines.

Baricitinib is a selective and reversible inhibitor of Janus kinase (JAK)1 and JAK2, which inhibits Janus kinase (JAK) enzymes, which are intracellular enzymes involved in stimulating hematopoiesis and immune cell function through a signaling pathway. JAKs activates signal transducers and activators of transcription (STATs), which regulate gene expression and intracellular activity.

Always take OLUMIANT 4 exactly as directed by your doctor. Tell your doctor if you have liver, kidney or heart problems, are pregnant or breastfeeding. This medicine is not recommended for use in children and adolescents below 18 years of age. The common side effects are headache, nausea, vomiting, cough and infections.

USES OF OLUMIANT 4

• Treats rheumatoid arthritis and atopic dermatitis (atopic eczema)

HOW OLUMIANT 4 WORKS

For rheumatoid arthritis, OLUMIANT 4 works by reducing the activity of an enzyme called Janus kinase, which is involved in inflammation. By reducing the activity of this enzyme, it helps to reduce pain, stiffness and swelling in your joints, tiredness and helps to slow down the damage to the bone and cartilage in the joints.

For atopic dermatitis, OLUMIANT 4 works by reducing the activity of Janus kinase enzyme, and helps to improve the condition of skin and reduce itching. It also helps to improve your sleep disturbance (due to itch) and overall quality of life.

DIRECTIONS FOR USE

Always take OLUMIANT 4 exactly as your doctor has told you. Swallow this medicine with a glass of water and do not crush or chew.

SIDE EFFECTS OF OLUMIANT 4

HOW TO MANAGE SIDE EFFECTS

Nausea:

Stick to regular meals and do not eat spicy foods.

Headache:

Rest and drink plenty of fluids. Apply a wet or cold cloth to forehead and rest in a quiet, comfortable, dark room.

Stomach pain:

Place a warm bottle or heated bag on your abdomen and drink plenty of clear fluids and water.

WARNING & PRECAUTIONS

INTERACTIONS

Tell your doctor if you are taking,

• Probenecid (used for gout)
• Injectable anti-rheumatic medicine
• Targeted biologic (antibody) therapies
• Azathioprine, tacrolimus, ciclosporin (used to control the body’s immune response)
• Ruxolitinib
• Non-steroidal anti-inflammatory medicines, opioids (treats pain)
• Corticosteroids (treats inflammatory conditions)