Numlo-D 5 Tablet (S-Amlodipine 5mg / Hydrochlorothiazide 12.5mg)

Numlo-D 5 Tablet

Numlo D 5 Mg/12.5 Mg Tablet is used to treat angina, high blood pressure and coronary heart disease. It is recommended in case of heart failure if other medications fail to work. Numlo D 5 Mg/12.5 Mg Tablet is the key ingredient of this medicine. It increases the myocardial oxygen delivery in patients with vasospastic angina.

Numlo D 5 Mg/12.5 Mg Tablet belongs to the class of a calcium channel blocker that inhibits calcium ion from entering the slow channels of vascular smooth muscle and myocardium during depolarization. This leads to cause relaxation of coronary vascular smooth muscle and coronary vasodilation.

The medicine should be taken as per the dosage on the prescription. Overdosage of the drug can lead to complications. Depending on the effects the drug has on a patient, the doctor may make variations to the dosage.

The medicine may not be safe to use during pregnancy or breastfeeding. Dosage should be low for elderly people and for those with liver problems. If you have heart problems then intake of Numlo D 5 Mg/12.5 Mg Tablet may increase your health problems.

The primary cardiac symptoms of calcium blocker overdose includes hypotension and bradycardia. The hypotension is caused by peripheral vasodilation, myocardial depression, and bradycardia. Bradycardia results from sinus bradycardia, second- or third-degree atrioventricular block, or sinus arrest with junctional rhythm.

Intraventricular conduction is usually not affected so QRS duration is normal (verapamil does prolong the P-R interval and bepridil prolongs the Q-T and may cause ventricular arrhythmias, including torsade de pointes).

In a few reported cases, overdose with calcium channel blockers has been associated with hypotension and bradycardia, initially refractory to atropine but becoming more responsive to this agent when larger doses (approaching 1 gram per hour for more than 24 hours) of calcium chloride was administered.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

Use

The most common use of this medication is:

Hypertension

Angina Pectoris

Side Effects

Following are some of the common side effects that may occur:

Peripheral Edema

Flushing

Palpitations

Headache

Rash

Pruritus

Sexual Dysfunction

Nausea

Abdominal Pain

Dyspepsia

Gingival Hyperplasia

Muscle Cramps

Weakness

Shortness Of Breath

Hypotension

Syncope

Insomnia

Weight Gain

Flatulence

Constipation

Vertigo

Urticaria

Agitation

Gastritis

Dosage

Missed Dose instructions

The missed dose should be taken as soon possible. It is advisable to skip the missed dose if it’s already time for your next scheduled dose.
Overdose instructions

Seek emergency medical treatment or contact the doctor in case of overdose.

Work

Numlo D 5 Mg/12.5 Mg Tablet works by inhibiting calcium ion from entering the “slow channels” or select voltage-sensitive areas of vascular smooth muscle and myocardium during depolarization, producing a relaxation of coronary vascular smooth muscle and coronary vasodilation; increases myocardial oxygen delivery in patients with vasospastic angina.