Macpril H 5 Tablet (Ramipril 5mg / Hydrochlorothiazide 12.5mg)

Description

Macpril H (12.5/5 mg) Tablet is a combination of Hydrochlorothiazide and Ramipril. This medicine is used for the treatment of high blood pressure. It works by relaxing your blood vessels. This helps your heart to pump blood easily and increases water excretion from your body, thus decreases high blood pressure. Therefore, this medicine also reduces the risk of heart attack and stroke.

Macpril H (12.5/5 mg) Tablet has some side effects like cough, nausea, headache, dry mouth, and upset stomach. Due to the action of this medicine, you may experience frequent urination while taking this medicine, and it is not a side effect. Drink plenty of fluids while taking medicine to overcome muscle weakness, dry mouth, and extreme thirst.

Macpril H (12.5/5 mg) Tablet may cause dizziness, therefore avoid driving vehicles or operating machines. Rise slowly from sitting or lying position if you feel dizzy while on Macpril H (12.5/5 mg) Tablet treatment. If any of these side effects do not resolve with time or get worse, seek a doctor’s consultation at the earliest. Avoid taking this medicine if you are allergic to it.

Macpril H (12.5/5 mg) Tablet can be taken in the morning to avoid frequent urination at night. Do not stop taking this medicine suddenly as it can cause your blood pressure to rise, thereby increasing the risk of heart attack and stroke.

Macpril H (12.5/5 mg) Tablet should be used with caution if you have kidney disease, liver disease, or diabetes. Frequent monitoring of your heart, liver, kidney functions and electrolytes levels may be required to use this medicine safely. Let your doctor know if you are taking any other medicines before starting the treatment.

Macpril H (12.5/5 mg) Tablet is not recommended for use in children. Consult your doctor if you are pregnant, planning a pregnancy or are breastfeeding before using Macpril H (12.5/5 mg) Tablet.

Side effects

Major & minor side effects for Macpril H (12.5/5 mg) Tablet
Increased urination
Itching or rash
Abdominal and stomach pain
Dry mouth
Joint pain, stiffness, and swelling
Cramping
Blurred vision
Sweating
Dizziness
Unusual tiredness and weakness
Back pain
Chest tightness
Increased heartbeat
Cough
Diarrhoea
Vomiting
Decreased blood pressure

Uses of Macpril H (12.5/5 mg) Tablet

What is it prescribed for?
Hypertension
Hypertension or high blood pressure is a condition in which the force exerted by the blood on the blood vessel walls is high. Macpril H (12.5/5 mg) Tablet is used to reduce blood pressure.

Related Products

List of related products
Macpril H (12.5/2.5 mg) Tablet

When not to use?

Allergy
Avoid taking Macpril H (12.5/5 mg) Tablet if you are previously allergic to it. Seek medical attention if you see symptoms such as skin rash, swelling ( of face, lips, tongue, etc.), breathing difficulty, etc.
Anuria
Taking Macpril H (12.5/5 mg) Tablet in case of anuria (a condition where the kidney is unable to produce urine) is not recommended as it may cause kidney damage.
Renal artery stenosis
Renal artery stenosis is a condition in which the blood vessels that carry blood to your kidneys become narrow and restrict blood flow. Macpril H (12.5/5 mg) Tablet is not recommended if you have renal artery stenosis as it reduces the filtration capacity of your kidneys.
Aliskiren
Combined use of Macpril H (12.5/5 mg) Tablet together with Aliskiren is not recommended if you have diabetes and/or kidney impairment. Combined use of these medicines may increase the risk of side effects.
Angioedema
Use of Macpril H (12.5/5 mg) Tablet is not recommended if you have a history of angioedema (swelling in the lower layer of your skin). In such cases, you may be at an increased risk of angioedema while receiving the treatment. Consult your doctor if you have any concerns.

Warnings

Warnings for special population
Pregnancy
Macpril H (12.5/5 mg) Tablet is not recommended during pregnancy as it may affect your foetus. Consult your doctor if you are pregnant.
Breast-feeding
Macpril H (12.5/5 mg) Tablet may pass into your breastmilk. Hence, consult your doctor if you are breastfeeding.
General warnings
Liver disease
Macpril H (12.5/5 mg) Tablet should be used with extreme caution if you have liver disease due to an increase in the risk of side effects. Close monitoring of liver function is necessary while taking this medicine. Report any symptoms like confusion or jaundice [yellow skin discolouration due to increased level of bilirubin (blood pigment)] to your doctor on priority.
Volume and electrolyte depletion
Macpril H (12.5/5 mg) Tablet may alter the blood volume and electrolyte levels. This may cause dizziness, dry mouth, and acid-base imbalance. Close monitoring of blood pressure and electrolyte levels is recommended.
Kidney disease
Macpril H (12.5/5 mg) Tablet may cause azotemia (elevated levels of urea and other nitrogen compounds in your blood) if you have a history of severe kidney disease. Your doctor will closely monitor your kidney function or adjust the dose to use this medicine safely.
Hyperkalemia
Macpril H (12.5/5 mg) Tablet may increase the potassium levels in the blood (hyperkalemia). It should be used with caution in patients with hyperkalemia and potassium levels should be monitored regularly. Avoid potassium-rich foods (potatoes, bananas) and potassium supplements during treatment with this medicine.
Use in children
Macpril H (12.5/5 mg) Tablet is not recommended for use in children and adolescents below 18 years of age as the safety and efficacy of this medicine is not clinically established.
Cough
Macpril H (12.5/5 mg) Tablet may cause a persistent nonproductive cough. It is resolved when the medicine is discontinued.
Driving and operating machines
Macpril H (12.5/5 mg) Tablet may cause dizziness and a decrease in blood pressure. Avoid performing any activities that require high mental alertness like driving vehicles or operating machines.
Hypotension
Symptomatic hypotension (low blood pressure) may occur if there is volume depletion (excess loss of salt and fluid leading to reduced fluid volume) or if you are treated with high-dose diuretics (medication that increases the removal of water and salt from the body via urine). Correct this condition before initiating treatment with Macpril H (12.5/5 mg) Tablet.

Dosage

Missed Dose
If you missed a dose of Macpril H (12.5/5 mg) Tablet, take it as soon as you remember. If the next dose timing is near, skip the missed dose. Take your next dose at your usual time. Do not double the dose.
Overdose
Never take Macpril H (12.5/5 mg) Tablet more than the prescribed dose. If you suspect that you might have taken an overdose of this medicine, go to the emergency department of your local hospital.

General Instructions

Take Macpril H (12.5/5 mg) Tablet exactly as advised by your doctor.
Drink plenty of water and electrolytes to avoid dehydration.
Take Macpril H (12.5/5 mg) Tablet around the same time every day so that it is easy to remember.
Try taking this medicine during the daytime to avoid frequent urination at night.
It is given for the long term so do not stop taking this medicine without consulting your doctor.
To get maximum benefits from the treatment, you should also adopt lifestyle changes like eating a low sodium and low-fat diet, exercising regularly, quit smoking, etc.
Avoid potassium-rich foods like bananas, oranges etc. while taking Macpril H (12.5/5 mg) Tablet.
Monitoring of kidney function and electrolytes levels is necessary while taking Macpril H (12.5/5 mg) Tablet.
This medicine can cause dizziness so be careful while standing up from a sitting position.
Do not break, crush or chew the tablet in your mouth.