Human Mixtard 70/30 Suspension for Injection (Insulin Isophane/NPH 70% / Human Insulin/Soluble Insulin 30%)

• If you are allergic to insulin or any of the ingredients of this medicine
• If you are suffering from hypoglycemia (low blood sugar level).

• Low blood sugar (Hypoglycaemia)
• Lightheadedness
• Dizziness
• Anxiety
• Nervousness
• Tiredness
• Feeling hungry
• Visual disturbances
• Headache
• Shaking
• Sweating
• Pale skin
• Skin rashes
• Pain, redness, swelling at injection site.

How Does It Work?

• Insulin is crucial to allow entry of blood glucose into each cell of the body
• Inside the cell, this glucose is used as fuel
• In type 1 diabetes mellitus, the body fails to produce adequate insulin
• This leads to glucose accumulating in the blood and cause high blood glucose
• This medicine lowers blood sugars by stimulating glucose uptake by cells, tissue and muscles, especially by skeletal muscles and fat and by inhibiting glucose production by the liver.

• Take this injection as per the technique suggested by your doctor or nurse
• This injection is to be taken under the skin of the thigh or upper arm or abdomen
• Do not take this injection in vein or in muscles
• Pull a skin, fold up to take this injection
• Wait for at least 6 sec before removing the needle from the injection site
• Always rotate the site of injection, do not take concurrent injections at the same site.

Interactions with other medicines

• You may have symptoms of low blood sugar if you are taking other medicines for diabetes, depression (fluoxetine), medicines for fever and pain (salicylates), ramipril, lisinopril
• You may have high blood sugar if you are taking oral contraceptives, thiazide, steroids, thyroxine, medicines used to treat severe diarrhoea and abnormal growth of body organs like octreotide, lanreot…
• If you are taking a medicine pioglitazone to treat diabetes, be cautious, as some cases of heart attack and heart failure have been reported
• Some medicines block your body’s response to low blood sugar, so you may not experience symptoms like headache, hunger pangs, sweating, anxiety when your blood sugar drops. This can lead to a serious …

Interactions with food items

• This medicine is to be taken 15 mins before meals or after meals
• Maintaining a constant meal pattern is advisable when you are taking insulin
• Avoid skipping or delaying meals when you are taking insulin.

• Store between 2°C to 8°C in the refrigerator
• Do not freeze it
• Keep it out of the reach of children
• Do not open the carton of vials to protect it from light
• Any unused portion should not be stored and should be appropriately discarded.

Overdose

• Excess insulin will lead to low blood sugar levels, called hypoglycemia
• Symptoms like dizziness, fainting, sweating and tremors may be seen
•  If you have the blood glucometer with you, test immediately and confirm
• Whether or not you test your levels, it is important to take some glucose water/juice/eat sugar or chocolates immediately and then rush to your doctor.

Missed a Dose

• Missed dose may lead to high blood sugar levels which can cause symptoms like feeling thirsty, excessive urination, loss of appetite, drowsiness, fruity smell from breath, etc.
• If you missed any dose of medicine take it as soon as you remember
• If it’s time for your next dose then skip the missed dose and continue with your regular dose schedule
•  Do not take a double dose of medicine to compensate the missed one as taking double dose can cause a drastic fall in blood glucose which can be dangerous.