Coversyl 4mg Tablet (Perindopril erbumine 4mg)

INTRODUCTION

COVERSYL 4MG contains Perindopril which belongs to a group of medicines called ACE inhibitors. ACE inhibitors lowers blood pressure by widening blood vessels which allows the blood to flow more easily and reduces the effort needed to pump blood around the body. It is used to treat high blood pressure (hypertension), heart failure, kidney problems in diabetic patients with high blood pressure and also used if you have recently had a heart attack (myocardial infarction). Hypertension also called as high or raised blood pressure, is a condition in which the blood vessels have persistently raised pressure.

COVERSYL 4MG is long-acting angiotensin converting enzyme inhibitor. ACE is a peptidyl dipeptidase that catalyzes the conversion of angiotensin I to the vasoconstrictor substance, angiotensin II. Angiotensin II also stimulates aldosterone secretion by the adrenal cortex. The inhibition of ACE results in reducing stress on the heart and relaxes blood vessel so that blood flows more smoothly and the heart can pump blood more efficiently.

Take COVERSYL 4MG exactly as prescribed by your doctor. The dose you take will depend on your age, other medications you are taking and whether you have any kidney or liver problems. Do not drive or operate machinery while taking this medicine, since it may cause dizziness or weakness. This medicine is not recommended for use in children and adolescents up to the age of 18 years, pregnant women and breastfeeding mothers. The common side effects are nausea, vomiting, headache and dizziness.

USES OF COVERSYL 4MG

Treats blood pressure and heart failure
Reduces the risk of cardiac events

HOW COVERSYL 4MG WORKS

COVERSYL 4MG works by widening the blood vessels and makes it easier for your heart to pump blood through the body.

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DIRECTIONS FOR USE

Take COVERSYL 4MG as prescribed by your doctor. Swallow as a whole, do not crush or chew. It can be taken in the morning before a meal.

SIDE EFFECTS OF COVERSYL 4MG

SERIOUS
Yellowing of the skin or eyes (jaundice)
Swelling of the face, lips, mouth, tongue, throat
Difficulty in breathing
Severe dizziness or fainting (low blood pressure)
Skin rash starts with red itchy patches on face, arms or legs (erythema multiforme)
Inflamed pancreas
COMMON
Headache, dizziness
Vertigo
Pins and needles
Vision disturbance
Tinnitus (sensation of noise in the ears)
Light-headedness due to low blood pressure
Cough
Shortness of breath
Nausea, vomiting
Abdominal pain
Taste disturbances
Dyspepsia or difficulty of digestion
Diarrhoea
Constipation
Allergic reaction
RARE
Increased level of liver enzymes or high level of serum bilirubin
Worsening of psoriasis

HOW TO MANAGE SIDE EFFECTS

Nausea:

Stick to simple normal meals and do not eat rich or spicy foods.

Diarrhoea:

Drink plenty of fluids to avoid dehydration. ORS should be used to prevent dehydration.

Stomach pain:

Place a warm water bottle on your abdomen. Soak in a warm bath. Drink plenty of clear fluids and water.

Dizziness:

Get up and move around to feel awake, take small naps to edge off the sleepiness. Give your eyes a break to avoid fatigue and eat a healthy food to boost energy.

Vomiting:

Drink clear or ice-cold drinks. Eat light, bland foods and avoid fried, greasy, or sweet foods.

Constipation:

Add fruits, vegetables whole grains and other high-fiber foods to your normal diet.

INTERACTIONS

Inform your doctor if you are taking or have recently taken any other medicines, including medicines obtained without a prescription or the following,

Valsartan, telmisartan, irbesartan and aliskiren (used for high blood pressure)
Racecadotril (used to treat diarrhea)
Sirolimus, everolimus, temsirolimus (used to avoid rejection of transplanted organs)
Sacubitril, eplerenone, spironolactone and procainamide (used to treat heart conditions)
Triamterene, amiloride (potassium-sparing drugs)
Trimethoprim/sulfamethoxazole
Lithium and medicines to treat psychotic disorders
Ibuprofen (used for pain relief)
Insulin or metformin (to treat diabetes)
Baclofen (used to treat muscle stiffness)
Ciclosporin, tacrolimus (used to treat auto-immune disorder)
Trimethoprim (used to treat infections)
Estramustine (used in cancer therapy)
Allopurinol (used to treat gout)
Heparin (used to thin blood)
Ephedrine, nor adrenaline or adrenaline (used to treat low blood pressure)
Medicines to treat symptoms of rheumatoid arthritis