Zix-PG 200/75 Tablet (Aceclofenac 200mg/ Pregabalin 75mg)

Zix-PG 200/75 Tablet 10’S is a combination medicine used for the management of neuropathic pain. Neuropathic pain is a chronic progressive nerve disease that causes nerve pain due to nerve damage or a malfunctioning nervous system. The pain could be intermittent or continuous, which is felt as a prickling, stabbing, tingling, or burning sensation.

Zix-Pg 200/75Mg Tablet 10’S is a combination of two drugs: Pregabalin (anti-convulsant), and Aceclofenac (NSAID). Pregabalin works by changing how nerves send messages to your brain. Aceclofenac works by blocking the effect of a chemical messenger known as cyclo-oxygenase (COX) enzyme that makes another chemical ‘prostaglandins’ (PG). Prostaglandins play an important role in controlling pain and inflammation. By blocking the effect of COX enzymes, lesser PGs are produced. This reduces mild to moderate pain and inflammation at the injured or damaged site decreasing stiffness in joints. Together, Zix-Pg 200/75Mg Tablet 10’S helps to treat neuropathic pain (pain due to nerve damage).

Take Zix-PG 200/75 Tablet 10’S with or without food. Swallow Zix-Pg 200/75Mg Tablet 10’S as a whole with a glass of water; do not chew, or break the tablet. You are advised to take Zix-Pg 200/75Mg Tablet 10’S for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side-effects such as nausea, vomiting, stomach pain, diarrhoea, loss of appetite, heartburn, dryness in the mouth, dizziness, sleepiness, uncoordinated body movements. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Please do not stop taking Zix-Pg 200/75Mg Tablet 10’S without consulting your doctor as it could cause withdrawal symptoms. Do not take Zix-Pg 200/75Mg Tablet 10’S if you are pregnant or breastfeeding unless prescribed by the doctor. Women of child-bearing potential should use effective contraception. Zix-Pg 200/75Mg Tablet 10’S causes drowsiness and dizziness, so drive only if you are alert. Zix-Pg 200/75Mg Tablet 10’S should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with Zix-Pg 200/75Mg Tablet 10’S as it could lead to increased dizziness and sleepiness. Keep your doctor informed about your health condition and medicines to rule out any side-effects. Before taking this medicine to inform your doctor have a history of heart disease, severe kidney disease, disorders of the stomach or gut/bowel, diabetes.

Neuropathic pain

Zix-Pg 200/75Mg Tablet 10’S is a combination of two drugs: Pregabalin (anti-convulsant), and Aceclofenac (NSAID’s). Pregabalin belongs to a group of medications called ‘anticonvulsants’ used to prevent neuropathic pain (pain due to damaged nerves), fibromyalgia (musculoskeletal pain), and epilepsy (fits). It works by calming the damaged or overactive nerves in your body that may cause pain or seizures, thereby decreasing the number of pain signals sent out by damaged nerves in the body. Overall it reduces the pain which has been damaged or irritated due to conditions like chronic conditions, diabetes, trauma, or epilepsy. Aceclofenac belongs to a group of medicines called Non-Steroidal Anti-Inflammatory Drugs (NSAID’s) used to reduce and relieve pain, redness, and inflammation (swelling) in patients suffering from osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. Zix-Pg 200/75Mg Tablet 10’S works by blocking the effect of a chemical messenger known as cyclo-oxygenase (COX) enzyme that makes another chemical ‘prostaglandins’ (PG). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, lesser PGs are produced. This helps in reducing mild to moderate pain and inflammation at the injured or damaged site. Together, Zix-Pg 200/75Mg Tablet 10’S helps to treat neuropathic pain (pain due to nerve damage).

Take Zix-Pg 200/75Mg Tablet 10’S with or without food. Swallow Zix-Pg 200/75Mg Tablet 10’S as a whole with a glass of water; do not chew, or break the tablet. Based on your medical condition, your doctor will decide how long you need to take Zix-Pg 200/75Mg Tablet 10’S.

Store in a cool and dry place away from sunlight

• Nausea
• Vomiting
• Stomach pain
• Diarrhoea
• Heartburn
• Dryness in mouth
• Dizziness
• Blurred vision
• Weight gain
• Sleepiness
• Tiredness
• Uncoordinated body movements